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Products not made with Diethylhexyl Phthalate (DEHP) and Polyvinyl Chloride (PVC)

We're committed to the use of safe materials

As a healthcare provider, you want the best for your patients, from the treatments you select to the products you use. However, in everyday medical settings, products such as IV bags and tubing can contain up to 40% DEHP by weight, resulting in significant levels of exposure for neonates and other vulnerable patient populations.5

Small baby sleeping while in a hospital setting with a gentle adult hand resting on the baby's head.

Facts about DEHP and PVC

Fact 1: PVC has been determined to be a human carcinogen by the National Cancer Institute, Agency for Toxic Substances, Environmental Protection Agency, Disease Registry and the International Agency for Research on Cancer.4,5,6

Fact 2: The evidence of patient exposure to DEHP and other toxins during the course of clinical care is well established, and there is a continued need to reduce patient exposure.7

Fact 3: The Consumer Product Safety Commission has restricted eight phthalates, including DEHP, from children's toys because ingestion can cause harmful health effects.8

Fact 4: The State of California has determined that DEHP is a reproductive and developmental toxicant and a carcinogen and advises patients to request devices that do not contain DEHP when they are undergoing medical treatment.9

Who is at risk? 

Products not made with DEHP or PVC help protect susceptible populations, such as: neonates and pediatric patients, particularly males, pregnant and lactating women and patients undergoing chemotherapy.

Headshot of Angela Karpf, MD, Corporate Vice President, Medical Affairs at B. Braun Medical Inc.

“We know that with the right level of attention, resources and national resolve, far more can be done to protect the safety of patients and healthcare providers, as well as our environment. We should begin by prioritizing public policy changes that champion safe practices in the healthcare system.”

Angela Karpf, MD, Corporate Vice President, Medical Affairs

1 Karpf, A. MD. Making patient safety a policy priority. Modern Healthcare. February 2021.

2 Schettler, T. Polyvinyl chloride in health care. Health Care Without Harm. January 2020.

American Medical Association. (2016). Encouraging Alternatives to PVC/DEHP Products in Health H-135.945.

4 Vinyl chloride: what is vinyl chloride? National Cancer Institute. Reviewed December 28, 2018. Accessed November 12, 2021.

5 Public health statement: Vinyl Chloride. Agency for Toxic Substances and Disease Registry. July 2006. Accessed November 12, 2021.

6 Polyvinyl chloride and copolymers production: national emission standards for hazardous air pollutants (NESHAP) – 40 CFR 63 subparts J & H. U.S Environmental Protection Agency. Updated February 23, 2021. Accessed November 12, 2021.

7 NTP-CERHR Monograph on the Potential Human Reproductive and Developmental Effects of Di(2-Ethylhexyl) Phthalate (DEHP), National Toxicology Program, Department of Health and Human Services, Retrieved at:

8 Bornehag et al. 2004; Engel et al. 2010; Hauser and Calafat 2005; Hauser et al. 2006; Kimber and Dearmna 2010; Meeker et al. 2009a, 2009b; Mendiola et al. 2011; Swan 2008; Swan et al. 2005

9 OEHHA Science for Health California. Proposition 65 Warnings Office of Environmental Health Hazard Assessment: Di(2-ethylhexyl)phthalate (DEHP). June, 2017.

10 FDA CEDRH. Safety Assessment of Di(2-ethylhexly) Phthalate (DEHP) Released from PVC Medical Devices. FDA CEDRH 1 – 118, 2003.

11 EB Mallow and MA Fox. (2014). Phthalates and critically ill neonates: device-related exposures and non-endocrine toxic risks. Journal of Perinatology, 1-6.

12 Sharpe RM, Skakkebaek NE (2008) Testicular dysgenesis syndrome: mechanistic insights and potential new downstream effects. Fertil Steril 2008; 89(2 Suppl):e33-e38.

13 US Consumer Product Safety Commission (CPSC Prohibition of Children’s Toys and Child Care Articles Containing Specific Phthalates. October 27, 2017. Accessed December 17, 2021.

14 Desdoits-Lethimonier C, Albert O, Le Bizec B, Perdu E, Zalko D, Courant F, Lesné L, Guillé F, Dejucq-Rainsford N, Jégou B (3/2012) Human testis steroidogenesis is inhibited by phthalates. Hum Reprod; 2012 Mar 8. [Epub ahead of print]

15 Bornehag et al. 2004; Engel et al. 2010; Hauser and Calafat 2005; Hauser et al. 2006; Kimber and Dearmna 2010; Meeker et al. 2009a, 2009b; Mendiola et al. 2011; Swan 2008; Swan et al. 2005

16 Hannas BR, Furr J, Lambright CS, Wilson VS, Foster PM, Gray LE (2011) Dipentyl phthalate dosing during sexual differentiation disrupts fetal testis function and postnatal development of the male Sprague-Dawley rat with greater relative potency than other phthalates. Toxicol Sci 120(1):184-193.

17 Maas, B., Huber, C. & Krämer, I. Plasticizer extraction of Taxol®-infusion solution from various infusion devices. Pharm World Sci 18, 78–82 (1996).